Final Days of Planet Earth

Final Days of Planet Earth is a 2006 science fiction miniseries directed by Robert Lieberman and written by Roger Soffer. Starring Campbell Scott, Gil Bellows, and Daryl Hannah, the movie was produced by RHI Entertainment for the Hallmark Channel.

Liz Quinlan, now an employee of the mayors office, knows all too well the secret of the aliens. She is their Earth Queen. The citys highest representatives are her consorts. With police and government officials taken over by aliens masquerading as humans, Lloyd and Marianne realize they can trust no one, except William Phillips, the one man who knows the ultimate goal of the aliens. He also holds the mysterious key to their defeatits in his blood. He is the commander himselfthe sole mission survivor being held as prisoner. Lloyd and Marianne must find him before he becomes a victim of an unearthly experiment.

Source: Wikipedia